0390 Cracking the EEG Code on Insomnia: How Odds Ratio Product Architecture Relates to Number of Insomnia Symptoms

Abstract Introduction Objective markers of insomnia have remained largely elusive. Odds ratio product (ORP; a marker objective sleep quality), is currently being investigated for potential role in assisting diagnosis. Recent research has shown how patients with may present hyperarousal and be identified by looking at ORP architecture. In the current study, we aimed to investigate architecture, specifically time spent lowest two (deep sleep) last decile (full wakefulness) ORP, relate number symptoms. Methods 403 participants (age 46.3±12.3, range 18-79, 172 females) recorded their in-home PSG using Cerebra Sleep System completed questionnaires. quality was measured odds (ORP) derived from micro-analyzing frontal EEG channels. On questionnaires, reported whether they experienced any following symptoms least three times week: trouble falling asleep, staying waking up too early. Statistical analyses included as dependent variable multiple linear regression, deciles highest independent variables, age covariate separate model. Results 60 1 symptom insomnia, 82 2 symptoms, 68 3 The full model significant (F2,399=4.675, p=0.010, R=0.228, R2 adj=0.052) indicated that only predictor (t399=2.321, p=0.021, β=0.131) after controlling age. Time not (p >0.05). Conclusion decile, indicative wakefulness, positively associated Individuals reporting more wakefulness. deep This indicate low drive subjective complaints, which consistent etiology. Support (if any)